By Dr .Muhammad Mosleh Uddin 28 Aug, 2026

CPP (crrebral perfusion pressure)

CEREBRAL PERFUSION PRESSURE (CPP) Definition CPP = The effective pressure that drives blood flow through the brain. Formula CPP = MAP − ICP Where: CPP = Cerebral Perfusion Pressure MAP = Mean Arterial Pressure ICP = Intracranial Pressure 🔷 Normal Range CPP = 60–80 mmHg This is normal adult range 🔷 Important Thresholds ⬇️ CPP < 50 mmHg] → Risk of cerebral ischemia] ⬇️ CPP < 30 mmHg] → Severe cerebral hypoperfusion] → Very poor prognosis] ⬆️ CPP > 100 mmHg] → associated with increased cerebral blood flow and increased intracranial pressure (ICP) 🔷 Children CPP ≈ 60 mmHg Commonly cited minimum/target value Maintain adequate CPP to ensure sufficient: 📌 Cerebral oxygenation 📌 Prevention of secondary brain injury Note: 📌 CPP < 50 mmHg = Danger (risk of ischemic stroke) 📌 CPP > 100 mmHg (risk of cerebral edema)] 📌 CPP 60–80 mmHg = Target CPP Dr. Muhammad Mosleh Uddin FCPS trainee (Cardiology), MBBS (CMC)