By Dr .Muhammad Mosleh Uddin
•
28 Aug, 2026
CPP (crrebral perfusion pressure)
CEREBRAL PERFUSION PRESSURE (CPP)
Definition
CPP = The effective pressure that drives blood flow through the brain.
Formula
CPP = MAP − ICP
Where:
CPP = Cerebral Perfusion Pressure
MAP = Mean Arterial Pressure
ICP = Intracranial Pressure
🔷 Normal Range
CPP = 60–80 mmHg
This is normal adult range
🔷 Important Thresholds
⬇️ CPP < 50 mmHg]
→ Risk of cerebral ischemia]
⬇️ CPP < 30 mmHg]
→ Severe cerebral hypoperfusion]
→ Very poor prognosis]
⬆️ CPP > 100 mmHg]
→ associated with increased cerebral blood flow and increased intracranial pressure (ICP)
🔷 Children
CPP ≈ 60 mmHg
Commonly cited minimum/target value
Maintain adequate CPP to ensure sufficient:
📌 Cerebral oxygenation
📌 Prevention of secondary brain injury
Note:
📌 CPP < 50 mmHg = Danger (risk of ischemic stroke)
📌 CPP > 100 mmHg (risk of cerebral edema)]
📌 CPP 60–80 mmHg = Target CPP
Dr. Muhammad Mosleh Uddin
FCPS trainee (Cardiology), MBBS (CMC)